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Screening Nasopharyngeal Carcinoma With EBV Associated Biomarkers in Zhongshan City

Recruitingn/aAges 30 Years - 69 YearsAllZhongshan People's Hospital, Guangdong, China
NCT04085900 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study includes two cohorts: (1) a serological screening cohort; (2) a serological and EBV DNA screening cohort. All participants will be tested for EBNA1-IgA, VCA-IgA, BNLF2b total antibodies (P85-Ab), with additional plasma EBV DNA testing in the latter cohort. Screening positive participants will be followed up annually. All subjects will also be followed by record linkage to Cancer Register and Population Register.

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subject residents in Zhongshan City or Wuzhou City * Subject has no medical record of nasopharyngeal carcinoma * ECOG 0-2 * Subject is able to comprehend, sign, and date the written informed consent document to participate in the study. * Subject has psychical condition and well consciousness, and also accept and cooperate with the follow-up of this study. Exclusion Criteria: * Subject has heavy cardiovascular, liver or kidney disease. * Subject has contraindications to nasopharyngeal fiberoptic endoscopy.
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What it tests

  • Blood and saliva
  • P85-Ab, EBNA1-IgA, VCA-IgA
  • Consecutive EBV DNA testing
  • Fiberoptic endoscopy and biopsy
  • Fiberoptic endoscopy and biopsy
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Where

2 sites
Zhongshan People's Hospital
Zhongshan, China
Wuzhou Red Cross Hospital
Wuzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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