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Active Surveillance for Low Risk Prostate Cancer

Recruitingn/aAges 50 Years - 75 YearsMaleI.M. Sechenov First Moscow State Medical Universi…
NCT04146077 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

An active surveillance protocol for patients diagnosed low-risk prostate cancer will be held. We plan to use PSA (prostate-specific antigen) testing, DRE (digital rectal examination), TRUS (transrectal ultrasound), MRI (magnetic resonance imaging) and follow-up biopsies to monitor patients and detect cancer progression in time.

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📋 Eligibility rules (as published)
Inclusion Criteria: * prostate adenocarcinoma verified by at least 12 core biopsy * patient must understand the sense of research, agree to participate and sign a form of agreement * low oncological risk according to EAU (European Association of Urology) Guidelines: stage T1-T2a, PSA\<10 ng/ml, ISUP (International Society of Urological Pathologists score)=1 (Gleason score 3+3=6) * not more than 33% cores with adenocarcinoma Exclusion Criteria: * previous treatment of prostate cancer * other prostatic malignant neoplasms * other oncological diseases * treatment with 5-alfa-reductase inhibitors * patient's refuse to continue study * patient's desire to begin treatment
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What it tests

  • Not listed
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Where

1 site
Institute for Urology and Reproductive Health, Sechenov University.
Moscow, Russia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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