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Conservative Endometrioma Surgery

RecruitingNAAges 18 Years - 40 YearsFemaleUniversitaire Ziekenhuizen KU Leuven
NCT04151433 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To study which surgical technique offers better results in treating endometriomas in terms of ovarian reserve preservation. The 2 conservatives techniques used are: 1. The combined technique 2. CO2 laser vaporization only Ovarian reserve will be assessed by consecutive measurements of AMH serum levels before and after surgery.

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📋 Eligibility rules (as published)
Population: patients planned for laparoscopic CO2 laser surgery for endometriotic cysts. Inclusion Criteria: * Age: 18 - 40 years (both inclusive) * Unilateral endometriotic cysts with a mean diameter of \>=2.5cm and ≤8 cm, measured in 3 dimensions. * Presence of a contralateral endometrioma of ≤ 2cm is allowed * Complaining of infertility and/or pain * BMI ≤35 * Use of contraception (combined or Progesteron only) for at least 4 weeks before surgery Exclusion Criteria: * Incomplete surgery for the pelvis * Contra-indication for the use of contraception (combined or Progesteron only) * Use of GnRH analogues preoperatively and in the first 3 months postoperatively * (History of) hysterectomy * Prior unilateral oophorectomy * Pituitary/hypothalamic disorders * Suspected malignancy * Contralateral endometrioma of \>2 cm * AMH \<0.7 preoperatively * Pregnancy
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What it tests

  • Comparison between 2 different laparoscopic techniques in conservative surgical treatment of endometriomas (both arms are existing and accepted surgical strategies).
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Where

4 sites
GZA Sint-Augustinus
Antwerp, Belgium
Cliniques universitaires Saint-LUC (UCL)
Brussels, Belgium
UZLeuven
Leuven, Belgium
CHR La Citadelle
Liège, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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