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Comprehensive Aneurysm Management Trial

RecruitingNAAges 18 Years - anyAllCentre hospitalier de l'Université de Montréal (C…
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In plain words

What the trial is, and whether it could suit you

The uncertainty regarding the management of Unruptured Intracranial Aneurysms (UIAs) has not progressed in the last 30 years. The fundamental ethical basis for this study is that physicians should only offer a risky preventive treatment when it has been shown to be beneficial. Before that, such treatment should be offered as an RCT. The CAM trial offers a comprehensive framework, so that all patients confronted with the clinical dilemma can be offered participation. The principal questions to be addressed are : 1. do patients with UIAs, considered for curative treatments, have a better long-term clinical outcome with active treatment or conservative management? 2. when patients are considered ineligible for conservative management, and surgical and endovascular management are both judged reasonable, do patients with UIAs have a better long-term clinical outcome with surgical or endovas

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with at least one documented, intracranial subarachnoid aneurysm (cavernous aneurysms are excluded) Exclusion Criteria: * Patients with any intracranial hemorrhage, including SAH, within the previous 30 days * Patients with AVM-associated aneurysms * Patients unable to give informed consent
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What it tests

  • microsurgery; endovascular interventions
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Where

6 sites
University of Alberta Hospital
Edmonton, Canada
Daniel Roy
Montreal, Canada
Centre Hospitalier Régional Universitaire de Tours
Tours, France
ASST Ospedale Papa Giovanni XXIII
Bergamo, Italy
Ospedale Vito Frazzi
Lecce, Italy
Ospedale San Carlo Borromeo di Milano
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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