🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Magnesium Infusion for Pain Management in Critically Ill Trauma Patients

RecruitingPhase 4Ages 18 Years - anyAllUniversity of California, Davis
NCT04166877 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Magnesium is a naturally occurring mineral that is important for your body and brain. Magnesium sulfate (study drug) is a medication containing magnesium that is commonly used to improve low blood levels of magnesium. Magnesium sulfate has also proven to be successful in managing pain before and after surgery. However, this drug has primarily been used for pain control in patients undergoing surgery. Patients in the ICU with injuries also need good pain control. Using magnesium may assist in decreasing narcotic (pain reliever) requirements and provide another non-narcotic drug for pain control. The purpose of this study is to test the effectiveness of continuous, intravenous (into or within a vein using a needle) administration of magnesium sulfate for pain control in trauma patients admitted to the adult Intensive Care Unit. This will be compared to intravenous normal saline (salt solu

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * All trauma patients admitted to an adult intensive care unit * Signed informed consent * Hospital or trauma multimodal pain management order set used for pain management * Ages 18-99 Exclusion Criteria: * Admission to the Pediatric Intensive Care Unit. * Head Abbreviated Injury Score (AIS) of greater than 1 * Known heart failure with reduced ejection fraction (EF \< 40%) * Renal failure (GFR \< 60) * Cardiac arrhythmia (except for sinus tachycardia) * Greater than 5% TBSA burn injuries * Moderate to severe alcohol withdrawal protocol ordered for patient * Regular use of opioids in the week prior to injury * Receiving continuous infusion of opioids * Patients expected to require general anesthesia between 24 and 48 hours after admission (during study drug administration) * Patients unable to provide consent is unavailable * Patients unable to provide a pain score * Pregnancy * Prisoners
💊

What it tests

  • Magnesium Sulfate in Parenteral Dosage Form
  • Normal saline placebo
📍

Where

1 site
UC Davis Health
Sacramento, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy