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Vitamin D and Health Status of British African-Caribbean Women

Recruitingn/aAges 18 Years - anyFemaleUniversity of Surrey
NCT04179370 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Vitamin D deficiency remains a global public health issue (Wilson 2017). In the United Kingdom (UK). There is a lack of research looking at vitamin D status of the British African-Caribbean population. This population is particularly at risk to vitamin D deficiency due to possessing a skin type which hinders the production of vitamin D in the skin. Further, due to the geographical location of the UK, there is reduced ability to produce vitamin D due to the low sun exposure (Libon 2013 ). Our main source of vitamin D is through skin exposure to the sun. In the UK, the UV radiation is only strong enough in April-September (Wilson 2017) for the production of vitamin D to occur. In winter months, vitamin D needs to be consumed in food or supplement form. Vitamin D is essential for healthy bones and is associated with reduced risk of certain cancers and immune disorders (Wilson 2017). There i

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📋 Eligibility rules (as published)
Inclusion Criteria: * Women * British African-Caribbean Self-reported Having African ancestral origin and migrated via the Caribbean islands, or having at least one parent with African ancestral origin that migrated via the Caribbean * Living in England for \>2 months * Aged 18-35 or \>55 years * No significant health issues * Pre-menopausal (regular menstrual periods) or Post-menopausal (menstrual periods stopped for longer than 12 consecutive months) * BMI 18-30kg/m2 Exclusion Criteria: * Women in perimenopause or menopause * Pregnant or planning pregnancy during study period * Hypercalcaemia (\>2.5mmol/L) - assessed and excluded at baseline * Currently receiving treatment for medical conditions that are likely to affect vitamin D metabolism (osteoporosis, hormone replacement therapy, anti-estrogens treatment, antiepileptic drugs and breast cancer treatment) * Regular use of sun beds * Having a sun holiday one month prior to commencing study or plans for a sun holiday for more than 4 weeks within the study period * Women who take vitamin D or calcium supplements (or multivitamin supplements that contain these vitamins) - If potential participant agrees to stop supplement use to join the study, a wash-out period of 8 weeks prior to commencing the study is acceptable * Living in England for less than 2 months
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What it tests

  • N/A - no intervention. Observational study.
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Where

1 site
University of Surrey
Guildford, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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