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โ† Trials
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Effect of Giving Reduced Fluid in Children After Trauma

RecruitingNAAges 6 Months - 15 YearsAllColumbia University
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In plain words

What the trial is, and whether it could suit you

This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volumes of IV fluid. Recent studies in adults show that patients actually do better by giving less fluid. The investigators do not know if this is true in children and this study is designed to answer that question and provide guidelines for IV fluid management in children after trauma.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Trauma patients older than 6 months and younger than 15 years admitted to the pediatric intensive care unit (PICU) * Patients admitted to the PICU directly from the Emergency Department (ED) * Patients admitted to the PICU from the operating room (OR) * Patients transferred to PICU from outside facility ED (need to have been in ED 12 hours or less) Exclusion Criteria: * Patients transferred to PICU from outside PICU or inpatient floor * Patients transferred to PICU from outside facility ED if \>12 hours * Patients expected to be discharged from the PICU within 24 hours * Patient with congenital heart disease as defined by a congenital cardiac defect requiring surgery or medication * Patient with diagnosis of chronic cardiac condition (e.g. hypertension, cardiac arrhythmia) * Patients with chronic kidney disease as defined by an abnormality of kidney structure or function, present for more than 3 months, with implications to health * Post-operative transplant, cardiac, and neurosurgical patients * Patients with traumatic brain injury * Patients with any disease that may affect baseline blood pressure and heart rate (endocrine disorders, certain genetic disorders, mitochondrial diseases) * Hypotension requiring vasopressor therapy * If massive transfusion protocol initiated
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What it tests

  • Balanced crystalloid solution volume administration
  • Packed Erythrocytes Units, Blood Product Unit volume
  • Plasma volume
  • Platelets volume
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Where

4 sites
John R. Oishei Children's Hospital of Buffalo
Buffalo, United States
Columbia University Irving Medical Center NewYork-Presbyterian Morgan Stanley Children's Hospital
New York, United States
University of Rochester, Golisano Children's Hospital
Rochester, United States
Le Bonheur Children's Hospital
Memphis, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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