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Comparing Efficacy of Microwave Vs Embolization Treatment for Adenomyosis

RecruitingNAAges 30 Years - 55 YearsFemaleKarolinska Institutet
NCT04209127 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Single blinded randomized controlled study of symptom improvement after uterine artery embolization (UAE) versus ultrasound guided percutaneous/transvaginal microwave ablation, evaluated by validated questionnaires. Adenomyosis is a benign condition causing pain and bleeding disorders in many women. Hysterectomy has historically been the golden standard for treatment as well as (postoperatively) diagnosis of the disease. In accordance with refined diagnostic tools such as ultrasound and/or MRI, minimally invasive treatments for adenomyosis are being explored. We plan to compare two minimally invasive techniques: embolization of the uterine artery (a commonly used procedure) and microwave ablation of adenomyotic tissue (previously only in clinical use in China).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy women aged 30-55 with symptomatic adenomyosis * Premenopausal * Adenomyosis diagnosted by TVUS * Willing to comply with protocol Exclusion Criteria: * Body Mass Index \>35 * Treatment with anticoagulant/bleeding disorder * Contraindication for UAE or general anesthesia
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What it tests

  • Microwave treatment via needle antenna
  • Embolization of uterine artery or branches thereof (routine treatment where polyvinyl alcohol particles are released into the predefined bloodstream)
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Where

1 site
Danderyd Hospital
Stockholm, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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