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Loratadine for the Reduction of G-CSF Induced Bone Pain in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization

RecruitingEARLY Phase 1Ages 18 Years - anyAllRutgers, The State University of New Jersey
NCT04211259 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This early phase I trial studies how well loratadine works in reducing granulocyte-colony stimulating factor (G-CSF) induced bone pain in patients with multiple myeloma who are undergoing stem cell mobilization. Loratadine is an antihistamine that may help to reduce or control bone pain during the process of stem cell collection in patients with multiple myeloma.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient must be able to provide informed consent * Patients with confirmed diagnosis of multiple myeloma * Able to swallow and retain oral medication * All ethnic groups are eligible Exclusion Criteria: * Non-English speaking person * Patients undergoing haploidentical allogeneic hematopoietic stem cell transplant * Known allergies, hypersensitivity, or intolerance to any of the study medications, excipients, or similar compounds * Any medical complications or conditions that would, in the investigator's judgement, interfere with full participation in the study * On therapeutic dose of aspirin (doses greater than 81 mg) within 7 days prior to the start of the study
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What it tests

  • Loratadine
  • Placebo
  • Questionnaire Administration
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Where

2 sites
Rutgers Cancer Institute of New Jersey
New Brunswick, United States
RWJBarnabas Health - Robert Wood Johnson University Hospital, New Brunswick
New Brunswick, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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