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Thrombus Aspiration in STEMI Patients With High Thrombus Burden

RecruitingNAAges 18 Years - anyAllGuangdong Provincial People's Hospital
NCT04212494 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a prospective, multicenter, open-label, randomized, controlled, parallel group study, in which ST-segment Elevation Myocardial Infarction (STEMI) patients with high thrombus burden(TIMI thrombus grade ≥3) are included. Patients are randomized to be treated with or without manual thrombus aspiration(TA) during primary percutaneous coronary intervention(PPCI) by a ratio of 1:1.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≥ 18 years; 2. STEMI patients undergoing primary PCI within 12 hours after the onset of symptoms; 3. High thrombus burden after guidewire passes the lesion (TIMI thrombus grade ≥3); 4. Informed consent must be voluntary; Exclusion Criteria: 1. Haemodynamic instability or cardiogenic shock; 2. After thrombolytic therapy; 3. The predicted survival time is less than 6 months due to non-cardiac disease; 4. History of coronary artery bypass grafting; 5. Participate in other researches within 30 days; 6. Preoperative gastrointestinal bleeding or contraindications to dual antiplatelet therapy; 7. Patients were considered unsuitable by other researchers.
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What it tests

  • Thrombus aspiration
  • PCI Alone
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Where

50 sites
Fujian Provincial Hospital
Fuzhou, China
First People's Hospital of Foshan
Foshan, China
The Second People's Hospital of Nanhai District
Foshan, China
First People's Hospital of Shunde (Affiliated Hospital at Shunde, Southern Medical University)
Foshan, China
Guangdong Provincial People's Hospital
Guangzhou, China
Guangzhou Panyu Central Hospital
Guangzhou, China
Guangzhou General Hospital of Guangzhou Military Command
Guangzhou, China
The first Affiliated Hospital, Sun Yat-Sen University
Guangzhou, China

…and 42 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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