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Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome

RecruitingPhase 3Ages 18 Years - anyAllTanta University
NCT04217733 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Ethosuximide and pentoxifylline in the treatment of abdominal pain related to irritable bowel syndrome

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📋 Eligibility rules (as published)
Inclusion Criteria: * • Age ≥ 18 years, * Man and Women, Negative pregnancy test and effective contraception, * IBS defined by the Rome criteria IV * During the previous seven days the inclusion visit, average numeric rating scale (NRS) pain ≥ 4. * IBS Treatment stable for 1 month Exclusion Criteria: * • Breastfeeding * Diabetic patients * Significant liver function abnormalities (transaminases\> 3N, cholestasis) and moderate renal disease (MDRD \<60 ml / min) * Addiction to alcohol and / or drugs, * Antiepileptic drugs taken (epilepsy or chronic pain) * Chronic pain of greater intensity than that related to IBS, * Known Allergyto succinimides (ethosuximide, methsuximide, phensuximide) and pentoxifylline. * History or current severe depression (hospitalization, long-term antidepressant treatment) * Psychotic disorders,
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What it tests

  • pentoxyifylline
  • Mebeverine
  • ethosuximide
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Where

1 site
Sherief Abd-Elsalam
Tanta, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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