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Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass

RecruitingNAAges 18 Years - 80 YearsAllChina National Center for Cardiovascular Diseases
NCT04220047 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Surgical occlusion of the left atrial appendage (LAAO) is sometimes performed during the cardiac surgery to reduce long-term risk of stroke.A previous study found that LAAO may be associated with increased risk of postoperative atrial fibrillation.New-onset atrial fibrillation (NOAF) after coronary artery bypass graft is related to an increased short-term and long term risk of stroke and mortality.Marshall ligament amputation may reduce the occurence of atrial fibrillation. However, little is known whether this approach is justified during the coronary artery bypass graft.Therefore, this study aimed to investigate whether LAAO and Marshall ligament amputation during off-pump coronary artery bypass was associated with reduced risks of postoperative new-onset atrial fibrillation and stroke.

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📋 Eligibility rules (as published)
Inclusion Criteria: * isolated first off-pump coronary artery bypass Exclusion Criteria: * Preoperative atrial fibrillation or a history of atrial fibrillation; * Concurrent cardiac or non-cardiac surgery * Intraoperative convert to bypass bypass surgery * Emergency surgery * History of previous cardiac surgery * Severe organ dysfunction
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What it tests

  • Left Atrial Appendage Resection and Marshall Ligament Amputation
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Where

1 site
Fuwai Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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