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Early Intervention in Infants With Cerebral Palsy

RecruitingNAAges 8 Weeks - 20 WeeksAllUniversity of Copenhagen
NCT04250454 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Contractures are a frequent cause of reduced mobility in children with Cerebral palsy (CP) already at the age of 2-3 years. Reduced muscle use and muscle growth have been suggested as key factors in the development of contractures, suggesting that efficient early prevention will have to involve stimuli that can facilitate muscle growth already before the age of 1 year. The present study protocol was developed to assess the effectiveness of an early intervention program, CONTRACT, on muscle growth and mobility in children at very high risk of CP compared with best standard care.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Infants younger than 17 weeks CA with suspicion of brain lesion determined from a medical assessment, by MRI or ultrasound scan or abcent fidgety movements (FM) determined as part of General Movement Asessement (GMA) will be included. The brain lesion should be rated severe enough by the clinician to have informed the parents of the associated risk of CP. Exclusion Criteria: * Infants otherwise eligible but with severe genetic abnormalties, severe heart problems, metabolic diseases, or still hospitalized will not be selected for the study.
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What it tests

  • CONTRACT
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Where

1 site
Elsass Foundation
Charlottenlund, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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