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Proximal Row Carpectomy vs Four-corner Fusion for Osteoarthritis of the Wrist

RecruitingNAAges 18 Years - 75 YearsAllTöölö Hospital
NCT04260165 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Study purpose is to compare the outcome after proximal row carpectomy (PRC) vs four-corner fusion (FCA) for SLAC/SNAC II-III type osteoarthritis (OA) in a double-blinded randomized controlled study setting. Patients with radiologically and clinically confirmed OA are randomized (1:1 computer generated sequence with random block size) to two parallel groups and will undergo either PRC or FCA. The study will be patient and assessor blinded. Baseline data is collected preoperatively and is followed by a follow-up visits at 2 and 6 weeks, 3, 6, 12 months, and 5, 10 years after the intervention. Unveiling of the allocation is at 12 months post-intervention.

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📋 Eligibility rules (as published)
Inclusion Criteria: * SLAC/SNAC II-III * Age 18 - 75 * Symptom duration \> 3 months * American Society of Anaesthesiologists physical status (ASA) I-II Exclusion Criteria: * Patient eligible for SL reconstruction or scaphoid * Ulnocarpal/pancarpal arthritis * Lunate fossa, proximal lunate arthrosis or both * Age \<18 or \>75 years * Rheumatoid arthritis * Heavy smoking (\> 20 cigarettes per day) * Condition or medication affecting bony healing (eg diabetes mellitus with poor glycemic control, malnutrition, use of per oral corticosteroids) * Alcohol or drug abuse * Neurological condition affecting upper limb function
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What it tests

  • Proximal Row Carpectomy
  • Four-corner fusion
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Where

5 sites
Töölö Hospital (Helsinki University Hospital)
Helsinki, Finland
Central Hospital of Central Finland
Jyväskylä, Finland
Kymenlaakso Central Hospital
Kotka, Finland
Tampere University Hospital
Tampere, Finland
Turku University Hospital
Turku, Finland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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