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Effects of a Specific Substance in Smokers

RecruitingNAAges 21 Years - 40 YearsAllOregon Health and Science University
NCT04281979 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Although rates of cigarette use are declining, the proportion of nondaily smokers is rising, particularly among young adults. Among young adults, nondaily smoking is associated with negative health consequences and, for some, may lead to the establishment of life-long smoking patterns. The goal of this project is to understand the behavioral, psychological and neurobiological factors that contribute to cigarette use in nondaily smokers to aid the development of tailored evidence-based interventions.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Participants must be 21-40 years old * Right-handed * Fluent in English * Report smoking cigarettes or e-cigarettes 1-27 days in the past month * Report binge drinking based on NIAAA criteria (5 or more drinks per occasion for males, 4 or more drinks per occasion for females) at least 1 time in the past 90 days without adverse incident Exclusion Criteria: * Seeking treatment for substance use (e.g. nicotine or alcohol use) * Moderate or Severe Nicotine Dependence * Current alcohol use disorder * Illicit substance use other than marijuana use in the past year * Marijuana use more than 10 times in the past year * Major neurological or medical illness - Significant head trauma - Current use of medication affecting the central nervous system * MRI contraindications (e.g. irremovable metal on the body or pregnancy)
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What it tests

  • Study Agent
  • Placebo
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Where

1 site
Oregon Health and Science University
Portland, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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