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Leptospirosis Registry - LeptoScope

Recruitingn/aAges any - anyAllUniversity of Cologne
NCT04288674 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Leptospirosis is a worldwide zoonotic diseases caused by pathogenic Leptospira spp. Human are accidental hosts, who acquired infections after exposition to animal urine, contaminated water or soil, infected tissue. Incidence of invasive leptospirosis disease causing acute kidney injury, acute respiratory distress syndrome (ARDS), myocarditis, hepatic dysfunction, hemorrhage and multi-organ failure, is globally increasing and there have been frequent outbreak situation throughout the world. Due to increasing outbreak situations and globally chances in species distributions, a worldwide surveillance in epidemiology and species distribution is urgently needed. The objective of the Leptospirosis Registry - LeptoScope is to overcome the lack knowledge on epidemiology, clinical course, prognostic factors and molecular characteristics for invasive leptospirosis disease.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Cultural, serological, molecular or histological evidence of invasive leptospirosis diseases * Clinical signs of disseminated leptospirosis disease without cultural, serological, molecular or histological evidence * Case controls: Matching procedures for controls: Particularly, case controls will be included at the same hospitals that conduced cases based on matching of demographics, underlying diseases and duration of hospitalization (i.e. one control per case, both in the same hospital). Exclusion Criteria: * Colonization or other non-invasive infection * Cultural, serological, molecular or histological evidence without dissemination
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What it tests

  • Retrospective data collection of demographics
  • Retrospective data collection of underlying diseases
  • Retrospective data collection of duration of hospitalization
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Where

1 site
University Hospital of Cologne
Cologne, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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