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Characterization of Vaginal, Urinary and Fecal Microbiomes in Women with Recurrent Urinary Tract Infections

Recruitingn/aAges any - anyFemaleHadassah Medical Organization
NCT04305808 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The objectives are to evaluate whether variations in vaginal and/or urinary and/or fecal microbiome predispose postmenopausal women to recurrent cystitis. This will be explored using comparison of microbiome profiles between those with recurrent UTI compared to age-matched women without recurrent UTI.

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📋 Eligibility rules (as published)
Patients' inclusion criteria: * Menopausal status * Two or more documented, culture-positive infections in the last six months or ≥3 infections in the last year Patients' exclusion criteria * Neurogenic bladder condition * Known immunodeficiencies * Usage of antibiotics or probiotics within the previous month * Known renal calculi or anatomic malformations Control subjects- Inclusion criteria: * Menopausal status * Sterile urine cultures, normal urinalysis, and negative sexually-transmitted PCR urine assay Control subjects- Exclusion criteria: \- A prior history of UTIs or other urologic abnormalities.
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What it tests

  • Not listed
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Where

1 site
Hadassah Medical Center
Jerusalem, Israel
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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