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The Beneficial Effects of Naps on Motor Learning

Recruitingn/aAges 18 Years - 80 YearsAllNational Institute of Neurological Disorders and โ€ฆ
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In plain words

What the trial is, and whether it could suit you

Background: Memory consolidation is the process by which memories become stable, long-term representations in the brain. Consolidation of a motor skill is dependent upon sleep. Some research shows that daytime naps improve people s motor performance and memory retention. Researchers want to find out how daytime naps may contribute to learning and support consolidation of motor skill memories. Objective: To learn the role of memory replay during wakeful rest and sleep (naps) in retaining a newly learned skill. Eligibility: English-speaking adults ages 18 and older with chronic stroke, or healthy, right-handed, English-speaking adults ages 18-35 and 50-80 Design: Participants will be screened with: * medical history * neurological history * medicine review * medical exam * neurological exam. Participants will have a magnetic resonance imaging (MRI) scan of the brain. For this, the

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
* HEALTHY VOLUNTEERS: INCLUSION CRITERIA: * Age 18-35 (Arm 1) or 50-80 (Arms 2). * English speaking. * Clear right-hand dominance (\>74 on Edinburgh Handedness Inventory). * Normal neurological examination as determined by the screening clinician. EXCLUSION CRITERIA: * HCPS affiliated NIH staff (i.e. - staff from our section). * Current pregnancy. * Contraindications for MRI or MEG. * Use of sleep medications within 24 hours of Experimental Session participation. * Severe or progressive neurological, psychological or medical condition as determined by the screening clinician. STROKE PATIENTS: INCLUSION CRITERIA: * Age 18 or older * Willing and able to provide consent * Experienced a stroke 6 months ago or more that affected at least one of the upper extremities at time of stroke diagnosis * Ability to perform the study task as assessed during physical examination * English-speaking EXCLUSION CRITERIA: * HCPS-affiliated NIH staff (i.e. - staff from our section). * Current pregnancy * History of large stroke lesions in brainstem or cerebellum as determined by screening clinician * Severe or progressive neurological disorder other than stroke (e.g., Parkinson s disease or multiple sclerosis) as determined by the screening clinician * Uncontrolled heart, lung, kidney, gastrointestinal, metabolic, psychiatric, sleep, or endocrine disorders as determined by the screening clinician * Contraindications for MRI or MEG.
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What it tests

  • MRI system
  • MEG system
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Where

1 site
National Institutes of Health Clinical Center
Bethesda, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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