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Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke

RecruitingNAAges 21 Years - 100 YearsAllNorthwestern University
NCT04312269 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age at enrollment is 21 or older * Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening * Severe to moderate motor impairment (FMA-UE of 7-40) * At least some voluntary shoulder and elbow muscle activation Exclusion Criteria: * Inability to follow instructions of the MyoCI task * Visual impairment (such as hemianopia) preventing full view of screen * Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest) * Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study * Inability to understand or follow commands in English due to aphasia or other reason * Diffuse or multifocal infarcts in both hemispheres * Substantial arm pain preventing participation for 90 minutes a day * Spasticity treatment (pharmacological or Botox) within last 3 months * Ferromagnetic implants that are MRI incompatible
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What it tests

  • Targeted Memory Reactivation (TMR)
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Where

1 site
Northwestern University
Chicago, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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