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Cognitive Impairment in Ageing People

Recruitingn/aAges 50 Years - anyAllYamei Tang
NCT04360200 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Mild cognitive impairment (MCI) and neurocognitive disorder such as Alzheimer's disease (AD) and Vascular dementia (VaD) have become common diseases in the elderly. The burden of dementia is rising in China, with major medical, social and economic impacts. To address this important public health problem, cohort study on elderly cognitive disorders should be carry out. The methods of early prevention, early diagnosis and early treatment the cognitive disorders in elderly should be found to reduce the burden of the social and economic issue due to dementia. At present, the international corresponding guidelines have taken gene and brain imaging biomarkers as important indicators of dementia pathogenesis research, accurate diagnosis and targeted intervention. The study will construct a prospective cohort to establish database that provide not only comprehensive epidemiological data on the M

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients over 50 years old. 2. Sign informed consent. 3. According to DSM-IV, the diagnostic standard of dementia was not met. 4. The clinical dementia rating (CDR) was 0.5. Exclusion criteria: 1. Subjects with mental retardation. 2. Refuse to have blood sampling, imaging and other examinations. 3. Uncooperative subjects that have serious organic diseases, or have a history of mental illness, or have physical disability (including severe aphasia). 4. Contraindications of MR scanning. 5. Suffering from serious physical or mental illness.
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What it tests

  • Not listed
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Where

1 site
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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