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Influenza Vaccination, ACEI and ARB in the Evolution of SARS-CoV2 Infection

Recruitingn/aAges any - anyAllConsorci Sanitari de Terrassa
NCT04367883 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Some authors have proposed the use of the flu vaccine to reduce the severity of COVID-19 cases, while some have proposed the use of ACE Inhibitors (ACEI) or Angiotensin Receptor blockers (ARB), since this virus shares hemagglutinin as a transmission mechanism and acts on the ACE2 enzyme during infection. Other authors described how none of the elderly patients receiving antihistamines and azythromycin in two nursing homes in Toledo -Spain- during the first wave died or needed hospital admission, even considering that 100% of residents had a positive serological test after that wave. Other authors have described a positive evolution in patients receiving amantadine for their Parkinson's disease. The aim is to evaluate whether the admitted patients who are previously vaccinated or those who were already receiving these treatments showed a better evolution.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Hospital Admissions at the Hospital of Terrassa from March 1, 2020 for any cause. Exclusion Criteria: * None. * For comparison of percentage of Influenza vaccination, ACEI and ARB vs general population, patients from outside the reference area of the Terrassa Health Consortium would be excluded.
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What it tests

  • Antihistamine
  • Amantadine
  • ACEI
  • ARB
  • Influenza vaccine and COVID
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Where

1 site
Hospital de Terrassa
Terrassa, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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