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The Effect of Exposure to Aversive Non-verbal Vocalizations on Pain Tolerance

RecruitingNAAges 18 Years - 60 YearsAllCentre Hospitalier Universitaire de Saint Etienne
NCT04423874 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Humans produce non-verbal vocalizations (shouting, growling, screaming), laughter, ...) in various contexts that are likely to perform biological functions. and important social issues. Yet despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal vocalizations remain little studied and poorly understood including in humans. In this context, the investigators wish to examine how the perception of vocalizations non-verbal aversive behaviours influence pain tolerance in healthy adults.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Participant in good health * Affiliated or entitled participant in a social security scheme * Participant who received informed information about the study and co-signed, with the investigator, a consent to participate in the study Exclusion Criteria: * Chronic pain * High blood pressure or poor circulation * Cardiac or vascular disease, or a heart condition (including symptoms of Raynaud's syndrome) * Allergy or hypersensitivity to cold * Diabetes * Epilepsy * Pregnancy * Recent serious injury * Neurological or psychiatric condition known to affect pain tolerance (e.g., peripheral neuropathy, schizophrenia) * History of fainting or seizures * History of frostbite
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What it tests

  • Cold pressor task (CPT)
  • index NOL
  • Playback Experiments
  • Video-pupillometry
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Where

1 site
Centre Hospitalier Universitaire SAINT-ETIENNE
Saint-Etienne, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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