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Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

RecruitingNAAges 25 Years - 85 YearsAllUniversity of New Mexico
NCT04432883 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analysis/phonological components analysis treatment will be paired with the stimulation. Two assessment sessions will be pretreatment, 1 session immediately post-treatment, and 1 session at 3 months follow-up.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. aged 25-85 2. must be greater than 6 months post-stroke 3. must have a diagnosis of aphasia based on impaired performance on the Western Aphasia Battery-Revised, Boston Naming Test, or during discourse production 4. must be left-hemisphere dominant as demonstrated by aphasia onset subsequent to left hemisphere damage 5. must be stimulable for naming Exclusion Criteria: 1. comorbid neurological disease. 2. damage to the anterior right hemisphere. 3. significant mood disorder. 4. substance/alcohol dependence or abuse within the past year 5. presence of any implanted electrical device or contraindications to tDCS or MRI 6. recent medical instability (within 4 weeks) 7. pregnancy
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What it tests

  • Active Comparator: Experimental: Active cathodal tDCS + language training
  • Sham Comparator: Placebo cathodal tDCS + Speech and language
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Where

1 site
University of New Mexico Center for Brain Recovery and Repair
Albuquerque, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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