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Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery (PANDA V)

RecruitingNAAges 18 Years - 90 YearsAllNanjing Medical University
NCT04444349 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cardiovascular diseases are the leading causes of death and prescription drug use. Research on certain dietary supplements looks promising as a way to help reduce risk factors. Previous studies showed that CoQ10 levels were decreased in cardiovascular patients and worsening of mitochondrial dysfunction was observed. The overall objective of this study is to determine if supplementing with CoQ10 can reduce inflammatory risk factors in adults with cardiac surgery, independent of other dietary or physical activity changes.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult men and women * Who receive cardiovascular surgery * Agree to participate in the surgery and sign the informed consent form Exclusion Criteria: * Pregnant or planning on getting pregnant during the study * Contain a minimum of 2 traits of metabolic syndrome * Refused to participate in the surgery and refused informed consent
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What it tests

  • Coenzyme Q10
  • Standard Medical Therapy
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Where

4 sites
Beijing Anzhen Hospital
Beijing, China
The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, China
The First Affiliated Hospital of Nanjing Medical University
Nanjing, China
West China Hospital of Sichuan University
Chengdu, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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