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Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting

RecruitingNAAges any - anyMaleUniversity of Pittsburgh
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In plain words

What the trial is, and whether it could suit you

Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy. The purpose of this study is to test the safety and feasibility of these transplant technologies and restore fertility for these participants.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Male participant at least in Tanner stage 3 * Previously cryopreserved and stored testicular tissue/cells (frozen due to an infertility-risking diagnosis or treatment such as chemotherapy or radiation) available for autologous transplantation and grafting * Healthy enough to undergo anesthesia * Written clearance for the procedure from the patient's hematologist or oncologist to confirm the patient has finished treatment for primary condition and are clear to undergo autologous stem cell transplant Exclusion Criteria: * Participants considered to be high risk for surgical complications * Participants with a history of leukemia, lymphoma or testicular cancer or a cancer that likely involved testicles at the time of testicular tissue collection * Diagnosed with psychological, psychiatric, or other conditions which prevent giving fully informed consent.
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What it tests

  • Spermatogonial Stem Cell Transplant and Testicular Tissue Grafting
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Where

1 site
Magee-Womens Hospital
Pittsburgh, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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