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โ† Trials
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Pediatric Post-Approval Registry

Recruitingn/aAges 18 Years - 21 YearsAllInspire Medical Systems, Inc.
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In plain words

What the trial is, and whether it could suit you

This registry is a prospective, multi-center, single-arm study of pediatric subjects (ages 18-21 years) who are undergoing implant of the Inspire Upper Airway Stimulation (UAS) System for the treatment of moderate or severe obstructive sleep apnea (OSA). Implanted subjects will be followed for 5 years post-implant.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Subject is between 18 and 21 years of age; 2. Subject has a diagnosis of moderate to severe OSA (15 โ‰ค AHI โ‰ค 65) based on a recent sleep study; 3. Subject has documented failure of, or intolerance to, positive airway pressure treatments, despite attempts to improve compliance; 4. Subject is contraindicated for, or not effectively treated by, adenotonsillectomy; 5. Subject has followed standard of care in considering all other alternative/adjunct therapies; 6. Subject is willing and able to have stimulation hardware permanently implanted and to use the patient remote to activate the stimulation; 7. Subject is willing and able to return for follow-up visits, undergo sleep studies (including in-lab and at-home), and complete questionnaires related to the registry; 8. Subject is willing and able to provide informed consent. Exclusion Criteria: 1. Subject has a combination of central + mixed apneas \> 25% of the total apnea-hypopnea index (AHI); 2. Subject has any anatomical finding that would compromise the performance of upper airway stimulation, such as the presence of complete concentric collapse of the soft palate; 3. Subject has any condition or procedure that has compromised neurological control of the upper airway; 4. Subject is unable, or does not have the necessary assistance, to operate the patient remote; 5. Subject is pregnant or plans to become pregnant; 6. Subject has an implantable device that may be susceptible to unintended interaction with the Inspire System; 7. Subject has a terminal illness with life expectancy \< 12 months; 8. Any other reason the investigator deems the subject is unfit for participation in the registry.
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What it tests

  • Inspire Upper Airway Stimulation System
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Where

8 sites
Childrens Hospital of Colorado
Aurora, United States
Children's Healthcare of Atlanta
Atlanta, United States
Duke University
Durham, United States
Cincinnati Childrens Hospital
Cincinnati, United States
Children's Hospital of Philadelphia
Philadelphia, United States
Children's Hospital of Pittsburgh
Sewickley, United States
University of Texas Southwestern/Children's Hospital of Dallas
Dallas, United States
Children's Hospital of the King's Daughters/East Virginia Medical School
Norfolk, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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