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Preventive Effect of Limited Decompression on Adjacent Segment Following Posterior Lumbar Interbody Fusion

RecruitingNAAges 18 Years - 80 YearsAllPeking University Third Hospital
NCT04469387 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a prospective single-center study. Patients requiring posterior lumbar interbody fusion (PLIF) for degenerative disease are prospectively enrolled and followed. Patients enrolled in this study have asymptomatic pre-existing spinal canal stenosis at adjacent segment. This study will focus on the effects of preventative limited decompression at adjacent segment.

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📋 Eligibility rules (as published)
Inclusion Criteria: * A clear diagnosis of lumbar spinal stenosis, and surgical level of L4-S1 (The levels to be operated on were decided by matching the clinical symptomatology with the radiological findings of the spinal levels that needed decompression); * Patients have asymptomatic pre-existing spinal canal stenosis (cerebrospinal fluid occlusion grade=1) at adjacent segment. * Failed at least eight weeks conservative treatment; Exclusion Criteria: * Unstable factors (slip, rotation, lateral bending, etc.) in adjacent segment L3/4; * Preoperative sagittal and coronal imbalance of the spine; * Lumbar infection and/or tumor diseases; * A previous history of lumbar fusion surgery.
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What it tests

  • Limited decompressions at adjacent segment with asymptomatic pre-existing spinal canal stenosis
  • Responsible segments fused
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Where

1 site
Peking University Third Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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