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Impact of Sinus Surgery on Individuals With Cystic Fibrosis

Recruitingn/aAges 18 Years - 99 YearsAllUniversity of California, Los Angeles
NCT04469439 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old). 2. Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and/or sweat chloride 3. Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines 4. chronic rhinosinusitis symptoms persisting beyond initial medical treatment 5. Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment Exclusion Criteria: 1. Underwent endoscopic sinus surgery in past 12 months 2. Will obtain follow up care at non-participating institutions 3. Unable to complete follow-up surveys
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What it tests

  • Not listed
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Where

9 sites
University of California, Los Angeles
Los Angeles, United States
Stanford University
Stanford, United States
University of Colorado
Aurora, United States
National Jewish Health
Denver, United States
University of North Carolina
Chapel Hill, United States
Oregon Health Science University
Portland, United States
Medical University of South Carolina
Charleston, United States
Vanderbilt University Medical Center
Nashville, United States

…and 1 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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