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Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients

RecruitingNAAges 18 Years - anyAllHeart and Brain Research Group, Germany
NCT04493996 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Postoperative delirium (POD) and postoperative cognitive decline (POCD) can be observed after cardiosurgical interventions. Taken together, these postoperative neurocognitive dysfunctions contribute to increased morbidity and mortality and higher economic costs. Preoperative risk factors of postoperative neurocognitive dysfunctions, such as decreased neuropsychometric performance or decreased cognitive daily activities, can be interpreted as reduced cognitive reserve. The aim of this study is to build up cognitive reserves to protect against the development of POD and POCD through preoperative, home-based, cognitive training.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Elective cardiac surgery (coronary artery bypass surgery, aortic or mitral valve replacement/reconstruction, or combination surgery) with standardized extracorporeal circulation * A sufficiently good knowledge of German is necessary as cognitive training and neuropsychological tests are language-dependent Exclusion Criteria: * History of stroke and preexisting psychiatric or neurological disorders that may impair the neuropsychological performance
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What it tests

  • Cognitive training
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Where

1 site
Department of Cardiac Surgery, Kerckhoff-Klinik GmbH
Bad Nauheim, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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