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Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

RecruitingNAAges 18 Years - 85 YearsAllVanderbilt University Medical Center
NCT04502225 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective at lowering supine blood pressure, these approaches may be utilized to treat supine hypertension non-pharmacologically. Raising the head of the bed decreases the amount of blood returning to the heart due to the effects of gravity. In this case, the decreased blood return to the heart may decrease blood pressure.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with autonomic failure and with supine hypertension from all races * Males and females, between 18 to 85 years Exclusion Criteria: * All medical students * Pregnant women * High-risk patients (for example: heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction) * History of serious allergies or asthma.
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What it tests

  • Tilt
  • Elevated trunk
  • Tilt - In home
  • Elevated Trunk - In home
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Where

1 site
Vanderbilt University Medical Center
Nashville, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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