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The Utility of Thromboelastography in Traumatic Brain Injury

Recruitingn/aAges 18 Years - 80 YearsAllShanghai 6th People's Hospital
NCT04524637 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Hemocoagulation disorder is recognized to have crucial effects on hemorrhagic or ischemic diseases. Coagulation-related damages secondary to traumatic brain injury are common and severe secondary insults of head trauma and often leads to a poor prognosis. In this study, we sought to assess if posttraumatic hemocoagulation disorders determined using thromboelastography are associated with coagulation-related damages secondary to traumatic brain injury, and evaluate their influence on outcome among patients with head trauma. Based on above results, prediction models or risk scoring systems will be further developed and validated to predict coagulation-related damages secondary to traumatic brain injury.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients who are delivered to hospital within 24 hours after head trauma * Patients whose abbreviated injury score (AIS) for other body regions is 3 or less are considered to be isolated traumatic brain injury Exclusion Criteria: * Patients with existing prior neurological disease * Patients with known coagulation disorders * Patients on anticoagulants and medications known to affect coagulation function within 30 days before trauma * Patients receiving blood components prior to blood draw * Patients who deteriorate and die before determining whether coagulation- related damage exists
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What it tests

  • Not listed
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Where

1 site
Shanghai Sixth People's Hospital
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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