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A Danish ICD-study in Patients with Coronary Artery Disease Resuscitated from Ventricular Fibrillation

RecruitingNAAges 18 Years - anyAllCopenhagen University Hospital, Rigshospitalet
NCT04576130 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

DanICD is a randomized, controlled study to with the aim to assess whether there is a benefit of ICD-implantation in patients with coronary artery disease (including acute myocardial infarction), who survive cardiac arrest due to ventricular fibrillation/sustained ventricular tachycardia and undergo revascularization and with an LVEF above 35%.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with CAD and cardiac arrest due to VF/VT, where angiogram is performed with complete revascularization (PCI, CABG or hybrid coronary revascularization) before ICD implantation. Unfavorable artery for PCI (i.e., excessive vessel tortuosity or chronic total occlusion) or high-risk invasive treatment is not mandatory in order to achive complete revascularization. * Age ≥18 years * LVEF \>35% at the time of discharge. The most recent LVEF assessment on which the current medical treatment will be based at the time of entry into the study will be used as baseline LVEF. Exclusion Criteria: * Non-ischemic cause of cardiac arrest (i.e. ion channel diseases, non-ischemic cardiomyopathy) * Previous CABG within the last 3 months before index hospitalization * Life expectancy less than 1 year or severe neurologic outcome * Unable or unwilling to give informed consent * Pregnancy
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What it tests

  • Implantable cardioverter defibrillator
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Where

1 site
Copenhagen University Hospital, Rigshospitalet
Copenhagen, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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