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Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis

RecruitingPhase 4Ages 18 Years - anyAllMercy Medical Center
NCT04588077 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Investigators want to compare the seroconversion rates between two-dose and three-dose regimens of the hepatitis B vaccine (Heplisav B) among patients with cirrhosis, a randomized prospective study.

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📋 Eligibility rules (as published)
Inclusion Criteria: \- All the cirrhosis patients more than 18 years old presented to the hepatology clinic in Mercy Medical Center between 09/2020 and 07/2021 who do not have immunity against Hepatitis B (defined as anti-HBs titer \< 10 mIU/ml) will be recruited. Exclusion Criteria: * Anyone who has had a serious allergic reaction to a prior dose of the hepatitis B vaccine, a component of the hepatitis B vaccine, or yeast should not receive the hepatitis B vaccine. * Those who had previous exposure to hepatitis B. * Post liver transplant patients. * Less than 18 years old.
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What it tests

  • Heplisav-B Injectable Product, 2-dose regimen
  • Heplisav-B Injectable Product, 3-dose regimen
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Where

1 site
Mercy Medical Center
Baltimore, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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