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An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy

RecruitingPhase 1Ages 18 Years - anyAllM.D. Anderson Cancer Center
NCT04589624 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This trial investigates whether hyperpolarized magnetic resonance imaging (hpMRI) can predict treatment response in patients with thyroid cancer and other malignancies of the head and neck undergoing radiation therapy and/or receiving systemic therapy before surgery. An hpMRI is like a standard MRI but involves the use of an imaging contrast agent called hyperpolarized 13-C-pyruvate. Diagnostic procedures, such as hpMRI, may predict a patient's response to treatment and may help plan the best treatment.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Be willing and able to provide informed consent * Be informed of the investigational nature of this study * Be diagnosed with thyroid cancer and other malignancies of the head and neck with intent for treatment Exclusion Criteria: * Have a history of severe claustrophobia * Have electrically, magnetically or mechanically activated implants that would preclude magnetic resonance imaging (MRI) * Have a history of cardiac arrhythmia * Have an allergy to Gadavist intravenous contrast * Estimated glomerular filtration rate (eGFR) \< 30 * If female, be pregnant or breast feeding at time of consent
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What it tests

  • Hyperpolarized Carbon C 13 Pyruvate
  • Magnetic Resonance Imaging
  • Magnetic Resonance Imaging
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Where

1 site
M D Anderson Cancer Center
Houston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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