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The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia

Recruitingn/aAges 1 Day - anyAllKarolinska Institutet
NCT04598750 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a prospective observational study designed to evaluate Immature Platelet Fraction or Immature Platelet Count and Platelet Function Analyzer-100/200 Closure Time-ADP (in vitro bleeding time) as markers of bleeding risk in thrombocytopenic preterm neonates admitted to the Neonatal Intensive Care Unit.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Have a gestational age \<32 weeks and a birth weight ≥500 grams; * Have a platelet count \<100 x 109/L; and * Have a parent/guardian willing to provide written informed consent. Exclusion Criteria: * Are not expected to survive for \>24 hours by the Attending Neonatologist; * Are thought to have a familial thrombocytopenia or platelet dysfunction, based on family history or clinical presentation (associated congenital malformations, platelet morphology).
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What it tests

  • Not listed
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Where

8 sites
Boston Children's Hospital
Boston, United States
Beth Israel Deaconess Medical Center
Boston, United States
Intermountain Medical Center
Murray, United States
Utah Valley Hospital
Provo, United States
Amsterdam University Medical Centre
Amsterdam, Netherlands
Leiden University Medical Center
Leiden, Netherlands
Karolinska University Hospital Huddinge campus
Huddinge, Sweden
Karolinska University Hospital Solna campus, Astrid Lindgren Children's Hospital
Stockholm, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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