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โ† Trials
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Voluntary Activation During Isokinetic Contractions in Subjects with Neuromotor Disorders

RecruitingNAAges 18 Years - 70 YearsAllIstituto Auxologico Italiano
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In plain words

What the trial is, and whether it could suit you

Activation is the amount of voluntary recruitment of a muscle during voluntary contraction. Full activation implies the recruitment of all muscle fibres at their tetanic frequency. In healthy subjects, and even in sports performances, full activation may be rarely achieved despite a subjectively maximal effort. Highly decreased activation has been observed in patients affected by various orthopaedic and neurological disorders. In these subjects, paresis may be caused or aggravated by primitive impairments of the central nervous system and/or, by stimuli arising from peripheral damaged tissues that inhibit the corticospinal or the intraspinal recruitment of motoneurones ("arthrogenous muscle weakness"). There are numerous investigations in the literature on activation measured during isometric contractions, while they are substantially missing as far as isokinetic concentric contractions

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * age between 18 and 70 years old; * ability to sign the informed consent form; * ability to understand the instructions and to complete the motor task; * voluntary knee flexion-extension range of at least 70ยฐ; * maximal extension of angle \< 30ยฐ (0ยฐ=full extension, 180ยฐ sagittal tibio-femural angle). Exclusion Criteria: * pregnancy; * a history of epilepsy (to avoid the risk for seizures triggered by the stimuli); * Mini Mental State Examination โ‰ค27/30; * implanted electro-sensitive devices; * any orthopedic condition limiting the articular mobility or muscular strength of the lower limbs; * current treatment with oral anticoagulant therapy (to avoid the risk for muscle hemorrhage); * medium/serius osteoporosis (femoral Bone Mineral Density on the affected side, t-score \< (-3.5)); * familiarity with the testing method.
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What it tests

  • Pathologic group
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Where

1 site
Istituto Auxologico Italiano
Milan, Italy
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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