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Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

Recruitingn/aAges 12 Years - 18 YearsAllYale University
NCT04634643 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The main aim of the study is to discover the mechanisms underlying the pathophysiology of NAFLD in obese youth.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Good general health, taking no medication on a chronic basis; * age 12 to 18 years, in puberty (girls and boys: Tanner stage II-V); * BMI \>85th for obese cohort; Exclusion Criteria: * Baseline creatinine \>1.0 mg; pregnancy; * the presence of endocrinopathies (e.g. Cushing syndrome); * cardiac or pulmonary or other significant chronic illness; * adolescents with a psychiatric disorder or with substance abuse; * monogenic obesity syndromes; * use of drugs affecting intrahepatic fat content (e.g.; liraglutide, fish oil, etc.).
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What it tests

  • Usual diet and physical activity
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Where

1 site
Yale New Haven Hospital
New Haven, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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