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← Trials
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Integrated Diagnostics for Early Diagnosis of Liver Disease

Recruitingn/aAges 18 Years - anyAllManchester University NHS Foundation Trust
NCT04666402 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is an observational study that will explore the hypothesis that by combining data from patients with liver disease with novel blood biomarkers, single nucleotide polymorphism (SNP) analysis and faecal microbiome analysis. The Investigators will improve diagnosis of liver fibrosis compared to the current available diagnostic tools.

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📋 Eligibility rules (as published)
Inclusion Criteria: * All patients referred to Community Liver Assessment Clinic. * Male or female \> 18 years of age. * Females will be non-pregnant and non-lactating. Exclusion Criteria: * Age \< 18 years. * Pregnancy/breast-feeding. Women of childbearing potential (not \>2 years post- menopausal and/or not surgically sterilised) must have a negative blood serum pregnancy test. * Isolated bilirubinaemia. * Known pre-existing liver disease. * Acutely unwell. * Suspected malignancy.
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What it tests

  • Blood tests for Single Nucleotide Polymorphisms
  • Faecal microbiome analysis
  • Serum for diagnostic biomarkers
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Where

1 site
Manchester University NHS Foundation Trust
Manchester, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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