Safety and Efficacy of Stereotactic Aspiration Plus Urokinase in Deep Intracerebral Hemorrhage Evacuation

Inclusion criteria: 1. aged 40 years or older; 2. the duration from onset to the baseline computed tomography angiography (CTA) scan was between 6 to 24 hours; 3. patients with a spontaneous ICH in the deep brain parenchyma (≥1 cm from the cortical surface); with hematoma volume more than 25 ml (measured with the ABC/2 method); without hydrocephalus caused by intraventricular hemorrhage; without cerebral herniation and the benefit of surgical treatment was unknown; 4. The Glasgow Coma Scale (GCS) ranged from 9 to 15; 5. patients with motor deficits; 6. The modified Rankin Score (mRS) ranged from 0 to1 before onset. Exclusion Criteria: 1. ICH was caused by aneurysms, arteriovenous malformations, tumors, or trauma; 2. patients had a history of intracerebral hemorrhage or ischemic cerebral infarction; 3. patients had severe coagulation disorders with INR ≥ 1.5; 4. patients had severe underlying diseases, which may affect the outcomes; 5. pregnant and lactating patients; 6. patients refused to sign the informed consent and receive follow-up.