AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents

RecruitingNAAges 13 Years - 18 YearsAllMclean Hospital
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

A growing body of research implicates rumination as being a transdiagnostic risk factor involved in the development of depression and anxiety in youth. Critically, mindfulness meditation has shown significant promise in targeting rumination, and ultimately improving depressive and anxiety symptoms. Mindfulness apps offer a convenient and cost-effective means for accessing mindfulness training, while being interactive and engaging for youth. Despite their growing popularity among teens, strikingly little research has been conducted on these apps. Two critical questions have yet to be addressed: (1) what are the underlying neural and cognitive mechanisms that account for the beneficial effects of these apps and (2) for whom is app-based mindfulness well-suited. To address these gaps, adolescents (ages 13-18) will be randomly assigned to an app-delivered mindfulness course vs. a control con

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Both genders, all ethnicities (see Section: Inclusion of Women and Minorities) * Ages 13-18 years * Written informed assent/consent from adolescent and parent/guardian * English as a first language or English fluency * Right-handed * Personal iPhone or Android smartphone * CRSQ rumination subscale score * If on psychotropic medication, must be on stable dose for at least 2 months Exclusion Criteria: * History or current diagnosis of any of the following DSM-5 disorders: schizophrenia spectrum or other psychotic disorder, bipolar disorder, substance/alcohol use disorder within the past 12 months or lifetime severe substance/alcohol use disorder. * Systemic medical or neurological illness that could impact fMRI measures of cerebral blood flow * Failure to meet standard exclusion criteria for fMRI scanning (e.g. pregnancy, claustrophobia, cardiac or neural pacemakers, surgically implanted metal devices, cochlear implants, metal objects in the body) * History of seizure disorder, or head trauma with loss of consciousness \> 2 mins * Serious or unstable medical illness (e.g., cardiovascular, hepatic, renal, respiratory, endocrine, neurologic or hematologic disease) * Participants with active suicidal ideation will be immediately referred to appropriate clinical treatment. * Current or past treatment with mindfulness-based psychotherapy (e.g., MBCT, DBT or ACT) * Exposure to in-person or app-based mindfulness/meditation course (at least 300 mins of past practice)
๐Ÿ’Š

What it tests

  • Mindfulness (Headspace) App
  • Active Control Condition ("Recharge" condition delivered in Headspace app)
๐Ÿ“

Where

1 site
McLean Hospital
Belmont, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy