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Added Value of 18 FDG Pet-scanner in Diagnosis and Management of Subclinical Rejection in Kidney Transplant Patients

RecruitingNAAges 18 Years - anyAllUniversity of Liege
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In plain words

What the trial is, and whether it could suit you

The renal biopsy (RB) represents the gold-standard for the diagnosis of acute renal transplant rejection (AR), and allows early verification of a so-called "subclinical" rejection, ie without any clinical or biological abnormality detectable in a stable kidney transplant patient. The RB also makes it possible to certify a strictly normal renal histology and thus to motivate the withdrawal of corticosteroid therapy. It is this 3-month post-transplant protocol RB protocol that has been effective since 2007 at the CHU Liège. However, RB is an invasive procedure, contraindicated in patients taking anticoagulants, and carrying a significant risk of complications. The potential complications associated with RB motivate the identification and validation of other diagnostic means. In the present project, the investigators propose to study the relevance of positron emission tomography (PET), cou

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📋 Eligibility rules (as published)
Inclusion Criteria: * Kidney recipients aged over 18 and of all sexes Exclusion Criteria: * Pregnant patients * Polyomavirus nephropathy * Highly sensitised patients (historical or at 3 months Donor specific antibodies) * No corticosteroids withdrawal allowed (second kidney transplantation or primary disease)
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What it tests

  • 18FDG PET / CT
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Where

1 site
Antoine Bouquegneau
Liège, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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