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Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

Recruitingn/aAges 18 Years - anyAllKliniken Beelitz GmbH
NCT04706234 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.

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📋 Eligibility rules (as published)
Inclusion Criteria: * diagnosis of probable or possible multiple system atrophy according to current consensus criteria (Gilman et al. 2008) or * diagnosis of probable or possible PSP according to the the Movement Disorders Society (MDS) diagnostic criteria (Höglinger et al. 2017) or * diagnosis of Parkinson's disease according to the MDS diagnostic criteria (Postuma et al 2015) * Hoehn and Yahr Stage within the range of I-V or * diagnosis of motor neurone disease or * diagnosis of a neurodegenerative disease other than specified above AND underwent laryngopharyngeal assessment according to the systematic task protocol during FEES (Warnecke et al. 2019). Exclusion Criteria: \- Patients who do not sign the consent form
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What it tests

  • Not listed
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Where

16 sites
Department of Neurology and Department of ENT, Medical University Innsbruck
Innsbruck, Austria
Department of Neurology, Medical University of Ulm
Ulm, Germany
Movement Disorders Hospital - Kliniken Beelitz
Beelitz-Heilstätten, Germany
Department of Neurology, Medical School Hannover
Hanover, Germany
Department of Neurology, University Hospital Münster
Münster, Germany
Department of Neurology, University Hospital Carl Gustav Carus
Dresden, Germany
Department of Neueology Asklepios Klinik Stadtroda
Stadtroda, Germany
Asklepios Fachklinikum Stadtroda
Stadtroda, Germany

…and 8 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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