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Incidence of Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery

Recruitingn/aAges 65 Years - anyAllSir Ganga Ram Hospital
NCT04707794 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Postoperative delirium (POD) is the most common adverse neurologic complication that can occur in patients of any age. Its incidence varies across age groups and is substantially influenced by patient-related risk factors. POD occurs in 17%-61% of major surgical procedures. Several risk factors which contribute to the development of POD include age more than 60 years, pre-existing cognitive dysfunction, presence of comorbidities, sensorial deficits, malnutrition, polypharmacy, impaired physical mobility and frailty. Postoperative delirium has several wide ranging and adverse outcomes that are consistently associated with delirium such as mortality, increased length of hospital stay, and increased hospital costs. A recently devised tool for rapid assessment of delirium is the 4 A's test. It has now been validated for identifying delirium in the surgical population. The proposed prospectiv

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients of age \>65yrs * Either sex * ASA physical status I - III * Elective non-cardiac surgical procedures under general anesthesia * Clinical Frailty Score (CFS): 1-8 * Patients requiring at least 24 hours of postoperative inpatient care. Exclusion Criteria: * Clinical Frailty Score (CFS) of 9 * Patients diagnosed with dementia, severe psychiatric or neurological diseases * Recent surgery within past 3-months * History of recent head injury in the preceding 3 months * Patients with uncompensated cardiovascular disease, hepato-renal insufficiency and uncontrolled endocrine disease * Patients on anti-depressant, anti-anxiety, anti-convulsant and anti-parkinsonism medications * Preoperative haemoglobin \< 8 gm % and serum albumin \< 3.5mg/dl * Patient inability to give informed consent * Presence of preoperative delirium as assessed by 4A'S Test (score ≥ 4)
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What it tests

  • Sevoflurane
  • Desflurane
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Where

2 sites
Sir Ganga Ram Hospital
New Delhi, India
Sir Ganga Ram Hospital
New Delhi, India
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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