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Trifecta-Heart cfDNA-MMDx Study

Recruitingn/aAges any - anyAllUniversity of Alberta
NCT04707872 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood transplant recipient and the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from heart transplants.

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📋 Eligibility rules (as published)
Inclusion Criteria: * All heart transplant recipients undergoing a biopsy for clinical indications and protocol biopsies, as determined by their physician or surgeon, will be eligible to enroll in the study. * Patients are enrolled based on standard of care biopsies, including surveillance biopsies in high-risk patients, with informed consent. Exclusion Criteria: * Patients will be excluded from the study if they decline participation * Are unable to give informed consent. * Recipients of multiple organs.
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What it tests

  • MMDx diagnostic test
  • Prospera
  • HLA antibody
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Where

12 sites
Baptist Health Institute for Research and Innovation
Little Rock, United States
Tampa General Hospital, 409 Bayshore Blvd.
Tampa, United States
Columbia University Medical Center, Columbia Interventional Cardiovascular Care
West New York, United States
Montefiore Medical Center, 3319 Rochambeau Avenue, 2nd FL
The Bronx, United States
Annette C. and Harold C. Simmons Transplant Institute, BaylorScott&White Research Institute
Dallas, United States
Cardiovascular Medicine, University of Utah Health
Salt Lake City, United States
Cardiac Transplantation Laboratory, The Victor Chang Cardiac Research Institute
Darlinghurst, Australia
Division of Cardiology, University of Alberta
Edmonton, Canada

…and 4 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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