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Bone Marrow Aspirate Concentrate (BMAC)Treatment for Knee Osteoarthritis

RecruitingNAAges 45 Years - 75 YearsAllUniversity of California, San Diego
NCT04716803 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to investigate the safety and effectiveness of bone marrow aspirate concentrate (BMAC) in patients with moderate to severe osteoarthritis of the knee. BMAC provides a rich source of mesenchymal stem cells (MSCs) and is a stem cell-based therapy that has been reported to preserve or improve the structure of joints. The Angel System is the device used in this study to concentrate bone marrow from the patient and is intended to separate a mixture of blood and bone marrow and collect plasma rich platelets preoperative to a surgical procedure. The goal of this study is to identify whether BMAC can be an effective and safe treatment for patients with osteoarthritis of the knee.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Kellgren Lawrence radiographic grade IV 2. Need for a total knee arthroscopy by the patients primary care provider/or orthopedist. 3. Persistent pain in target knee that is unresponsive to standard of care including acetametaphine, non-steroidal anti-inflammatory drugs, physical therapy and/or intraarticular corticosteroids and/or hyaluronic acid preparations. 4. Males or females aged 45-75. Exclusion Criteria: \-
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What it tests

  • Bone Marrow Aspirate Concentrate
  • Angel Concentrated Platelet Rich Plasma (cPRP) System
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Where

1 site
University of California San Diego Koman Outpatient Pavilion
La Jolla, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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