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Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty

Recruitingn/aAges 18 Years - anyAllUniversity of California, Los Angeles
NCT04717869 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Frailty, the decline in physical and cognitive reserves leading to vulnerability to stressors is increasingly being recognized as a public health concern. Although multiple measures exist that can identify frail patients, very little is known about how or when to intervene. Sarcopenia, or the degree of muscle wasting, is closely correlated to frailty and patient outcomes. This is a prospective cohort study of critically ill patients to identify modifiable risk factors of sarcopenia, as potential targets to reduce frailty.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients admitted to the Surgical, Cardiothoracic or Neuro ICU * ICU stay longer than 24 hours Exclusion Criteria: * Patients with muscular or mitochondrial diseases affecting muscle quality or mass * Preexisting paralysis * Absence of lower limbs * Ongoing discussions about goals of care * Transfers from a skilled nursing facility * Children under the age of 18
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What it tests

  • Ultrasound
  • Biomarker Analysis
  • Frailty Index
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Where

1 site
Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine
Los Angeles, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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