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Investigating Inhibitory Control Networks in Parkinson's Disease

RecruitingNAAges 18 Years - anyAllUniversity of Alabama at Birmingham
NCT04735458 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain activity associated with these symptoms, and perform recordings of the surface of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Eligible for surgery based on multi-disciplinary consensus review * Have a diagnosis of Parkinson's disease or Essential Tremor * Have a diagnosis of medically-refractory movement disorder (Parkinson's disease, Essential Tremor, or dystonia) * Willingness to participate in the paradigms described in the protocol Exclusion Criteria: * Inability to provide full and informed consent * Age younger than 18 * Are not able to participate in study-related activities * History of prior ischemic/hemorrhagic stroke, subdural hemorrhage, or seizure
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What it tests

  • Procedure/Surgery: Response Inhibition and Deep Brain Stimulation in Parkinson's disease
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Where

1 site
University of Alabama at Birmingham
Birmingham, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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