Behavioral Comparison of Three Different Graft Materials to Increase Soft Tissue Thickness Around Dental Implants.

Inclusion Criteria: Patients referred to Department of Periodontology (CUO) in need of a single implant and need of soft tissue augmentation such as buccal defects, thin biotype, lack of keratinized tissue and aesthetic compromised situation. * The patient must be ≥18 years and able to understand the nature of the proposed surgery and must sign an informed consent. * The implant must be located between 2 fixed reference points (i.e. clinical crowns). * Anterior and premolar teeth (from premolar to premolar). * Enough crestal bone width to leave a minimum thickness of 2mm at the buccal bone plate when placing the implant. * Palate must have ≥2mm of thickness at premolar area. * Full mouth plaque and bleeding score \<20%. Exclusion Criteria: * Pregnant or lactation. * Active periodontal disease. * Previous soft tissue augmentation in the area. * Need of guided bone regeneration (GBR) during or after the placement of the implant. * Heavy smokers (\> 10 cigarettes per day). * Local or systemic conditions that would interfere with routine periodontal therapy (non-controlled diabetes mellitus, cancer, HIV, Chronic High dose steroid therapy, bone metabolic diseases, radiation, immunosuppressive disorders, liver function disorder, immunosuppressant disease, autoimmune disease). * Allergy to non-steroidal anti-inflammatory drugs. * Patients taking medications that cause gingival enlargement.