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A Non-pharmacological Cough Control Therapy

RecruitingNAAges 18 Years - 85 YearsAllWest Park Healthcare Centre
NCT04767074 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Coughing affects almost all individuals with ILD leading to physical, psychological and social distress and prevents individuals from performing their activities of daily living, working or socialising in public places. Unfortunately, there are no licensed medications available to treat chronic cough and the few drugs that have been tried resulted in little efficacy and significant side effects. Drug-free cough control interventions have shown promise in reducing the severity and impact of coughing on patients' lives but have not been tested in individuals with ILD. This study aims to explore the feasibility and effectiveness of a non-pharmacological cough control therapy, as an adjuvant of pulmonary rehabilitation, in patients with ILD and chronic cough (\>8 weeks in duration).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Individuals will be included if having confirmed diagnosis of any ILD by a physician (as per Canadian Thoracic Society's guideline for evaluating patients with fibrotic interstitial lung disease) and a chronic cough lasting more than 8 weeks in duration Exclusion Criteria: * self-reports of moderate or large sputum production * effective or suspected exacerbation of the respiratory condition in the past month * upper respiratory tract infection in the past month * use of angiotensin-converting enzyme inhibitor medication * changes in the prescribed medication in the previous month * evidence of traction bronchiectasis in the HRCT * evidence of other medical conditions that prevent performance of an exercise training program * unable to read or speak in English / unable to provide informed consent.
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What it tests

  • Non-pharmacological Cough control Therapy
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Where

2 sites
St. Joseph's Healthcare Hamilton
Hamilton, Canada
West Park Healthcare Centre
Toronto, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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