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Genetics of Central Nervous System Arteriovenous Malformations (GENE-MAV)

Recruitingn/aAges any - anyAllFondation Ophtalmologique Adolphe de Rothschild
NCT04772963 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cerebral and medullary arteriovenous malformations (AVMs) lead to arterial and venous networks to communicate pathologically, creating an arteriovenous shunt. The occurrence of intracranial haemorrhage is the most important prognostic factor of AVMs because it is associated with a significant morbidity and mortality. The genetic, molecular and cellular mechanisms that cause vascular malformations of the central nervous system are partially known and the influence of genetic damage on the prognosis of AVMs is poorly known.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient with a vascular malformation of the cerebral or medullary identified on diagnostic imaging (angio-CT, angio-MRI or diagnostic angiography) for which clinical monitoring alone or intervention (endovascular treatment, surgery or radiosurgery) is planned in the centres participating in the research. Exclusion Criteria: * Pregnant, parturient or breastfeeding woman
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What it tests

  • blood sample
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Where

1 site
HOPITAL FONDATION Adolphe de ROTHSCHILD
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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